Thursday, October 3

Adaptive Platform Trials Scientific Meeting 2024

Join the conference to explore strategies and approaches to the design, operation and implementation of adaptive platform trials.

By CanTreatCOVID

Date and time

Thu, Oct 3, 2024 9:00 AM - 5:00 PM EDT

Location

Chestnut Conference Centre

89 Chestnut Street Toronto, ON M5G 1R1 Canada

Refund Policy

Refunds up to 7 days before event

Eventbrite's fee is nonrefundable.

Agenda

9:00 AM

Welcome and introduction

9:10 AM

Overview of the basics of adaptive platform trials

Overview of the basics of adaptive platform trials (APTs) and suitable questions for an APT

9:50 AM

How to design an adaptive platform trial

- Platform structure (includes defining treatment arms, assessing patient eligibility status, and identifying patient characteristics or biomarkers that form the basis for stratification into subgrou...

10:30 AM

Break

10:45 AM

Analysis of data

Algorithms and methodologies for the analysis of data generated by adaptive trials

11:30 AM

Panel discussion: lessons from previous adaptive platform trials

12:00 PM

Lunch and networking

12:45 PM

Operational aspects of adaptive platform trials

- Registering your trial - Modular approach to protocol (master protocol & sub-protocols) - Research coordinator perspective: challenges and solutions, the importance of standardization, and the ...

1:30 PM

Panel discussion: real-world challenges in the operational aspects of APTs

Real-world challenges in the operational aspects of APTs and discuss strategies to address them

2:00 PM

Break

2:15 PM

Interactive mock REB meeting

Participants will review a short proposal idea for an adaptive platform trial, discuss it in the context of research ethics, and provide feedback

3:00 PM

Transparent consent in APTs

Approaches to explain APTs to patients and truly informed consent

3:45 PM

Participant engagement in APTs

Participant engagement and implementing Good Participatory Practices in APTs

4:15 PM

Funding strategies and models

Funding strategies and models to support the sustainability of APTs

5:00 PM

Closing remarks

About this event

8 hours

The APT Scientific Meeting is for clinical trialists, clinical investigators, statisticians, trial methodologists, health economists, trainees, policymakers, patient advocates, and anyone interested in using, designing, and implementing platform trials.

Learning objectives:

- Understand the key elements of designing and implementing an adaptive platform trial.

- Gain insights into the operational aspects of adaptive platform trials, such as protocol development, CRF design, data management, and the role of standardization and operational documents.

- Understand the importance of pre-trial model-based simulations and interim statistical analyses for adaptive platform trials.

- Learn about the ethical considerations, best practices, and the role of Research Ethics Boards (REBs) in operationalizing ethical guidelines throughout adaptive platform trials.

- Explore strategies for effective engagement and involvement of participants, including patients and other stakeholders, in the adaptive platform trial process.

Scientific committee members: Drs. Andrew Pinto, Benita Hosseini (Chair), Lisa Schwartz, Robert Fowler, and Shirin Golchi

Frequently asked questions

Who should attend the APT Scientific Meeting?

The APT Scientific Meeting is for clinical trialists, clinical investigators, statisticians, trial methodologists, health economists, trainees, policymakers, patient advocates, and anyone interested in the use, design and implementation of platform trials.

Can I submit an abstract?

Yes, abstract submissions are welcome. For more information and to submit, visit cantreatcovid.org/apt-meeting or email info@cantreatcovid.org.

Can I volunteer or participate as a speaker?

We appreciate your interest in contributing to the conference. Please contact our organizing committee at info@cantreatcovid.org to inquire about speaking at the APT Scientific Meeting. We welcome diverse perspectives and expertise.

Can attendees join online?

Yes. Registration for virtual attendance will open closer to the conference date. Attendees will have access to live and recorded sessions and the ability to participate in Q&A sessions.

Organized by

CanTreatCOVID

The Canadian Adaptive Platform Trial of Treatments for COVID in Community Settings (CanTreatCOVID) aims to identify effective, affordable and evidence-based medications for COVID that would reduce emergency department visits and hospital stays and help people feel better faster. The long-term goal of CanTreatCOVID is to find medications that prevent post-COVID condition, also known as long COVID.

$30 – $60